In hepatitis C, RNA is the most important and accurate method of determining the duration of the disease. This study allows us to determine the necessary method of treatment. For the diagnosis of the disease, several blood tests are usually used:
markers of hepatitis C-are used at the first suspected presence of the disease;
RNA - study of hepatitis C virus.
Viral hepatitis C is called an infectious disease that affects the liver. The main route of infection – ingestion of infected blood. This can happen during a blood transfusion due to non-sterile medical instruments. Sometimes the disease is transmitted through unprotected sexual intercourse or during childbirth from an infected mother to a child.
The disease is dangerous for its chronic form. It can last a lifetime and causes serious liver dysfunction, cirrhosis or cancer. About 80% of infected people have a chronic form of the disease.
The main danger of the disease is a hidden form of the disease, without obvious symptoms. Sometimes the temperature rises, there is nausea and vomiting, physical weakness, fatigue, loss of appetite and weight. For liver tissue in this disease is characterized by a small seal, due to which its cells are malignant degenerate. The development of the disease is very slow, and can occur for several decades.
What is hepatitis C RNA and why should it be investigated? Any virus is a tiny particle of RNA. The definition of RNA viruses is essentially a biological study of blood cells in order to determine the presence in the organism the genetic material of the virus of hepatitis C. For this used the method of polymerase chain reaction. There are 2 types of tests to determine the RNA of hepatitis C virus.
A qualitative test determines the presence of the virus in the cells of the circulatory system. A positive test indicates that the virus is actively multiplying in the blood, infecting healthy liver cells. Antiviral therapy involves the passage of this test in the period of 4, 12 and 24 weeks of treatment. After the termination of treatment, the analysis is also done after 24 weeks, and then once a year.
A quantitative test is performed to determine the concentration (specific content) of hepatitis C virus in the blood. That is, the amount of viral RNA in a certain amount of blood is determined. The severity of the disease does not depend on the amount of the virus. This analysis is performed to determine the infectious degree of the disease. It determines the success of treatment and the duration of antiviral therapy, and is carried out before it starts, and 3 months after the end.
Today 10 known genotypes of hepatitis C virus Genotyping of viral RNA to diagnose the presence of different types of the disease. The genetic type of the virus is crucial in determining the timing of therapy. Properly selected treatment can give a 90% guarantee of full recovery.